Dr.Ali CHAMSEDDINE

Consultant Medical Oncologist and Clinical Hematologist

Dr. Ali Chamseddine is a Consultant Medical Oncologist and Clinical Hematologist with over 15 years of experience in comprehensive cancer care. He is French Board-certified in both Medical Oncology and Clinical Hematology. His training in both France and the United States equips him with international expertise that enhances his practice. He also holds a PhD in Public Health and Molecular Oncology from the prestigious University of Paris-Saclay, where he was awarded the highest honors, summa cum laude. His doctoral research developed novel statistical methodologies for assessing treatment efficacy in advanced gastric cancer, contributing to clinical trial design and evidence generation. Dr. Chamseddine completed his residency and fellowship in Oncology and Hematology at the University of Rouen and the Henri-Becquerel Cancer Center. He later worked as Senior Assistant Physician at Gustave Roussy Cancer Center in Villejuif, France, Europe’s leading cancer institute, before pursuing a postdoctoral fellowship in leukemia at MD Anderson Cancer Center in Houston, USA, recognized as the world’s foremost cancer center. Upon returning to France, he held senior consultant roles at Gustave Roussy Cancer Center, where he led the Jules Verne Unit within the International Department of Oncology, as well as at the Ambroise Paré-Hartmann Group and Cochin Hospital (AP-HP, Paris), focusing on digestive and solid tumor oncology. In the UAE, Dr. Chamseddine was the founding Head of Oncology at Dr. Sulaiman Al Habib Hospital in Dubai, where he established the department and introduced advanced oncology services. He is a recognized expert in precision oncology, with strong academic credentials in immuno-oncology, pharmacogenomics, clinical research, and personalized medicine. Dr. Chamseddine has published over 45 peer-reviewed publications, including a letter in The New England Journal of Medicine, which highlights his contributions to significant clinical discussions in oncology. At Al Zahra Hospital Dubai, Dr. Chamseddine treats the full spectrum of solid tumors and hematologic malignancies, with a particular emphasis on gastrointestinal, breast, lung, genitourinary, and gynecologic cancers, as well as soft tissue sarcomas, lymphomas, and multiple myeloma. He routinely integrates molecular profiling, liquid biopsy, and pharmacogenomic-guided strategies into highly personalized treatment plans. At Al Zahra Hospital Dubai, Dr. Chamseddine collaborates with esteemed colleagues in the multidisciplinary Cancer Center, delivering state-of-the-art, compassionate and individualized cancer care. Fluent in French, English, and Arabic, Dr. Chamseddine provides care for both local and international patients. He is an active member of several international professional bodies, including ESMO (European Society for Medical Oncology), ASCO (American Society of Clinical Oncology), ASH (American Society of Hematology), and EHA (European Hematology Association), and sits on the scientific committee of the Francophone Federation of Digestive Oncology (FFCD). He is also the founder…

Languages

Qualifications

Medical Degree (MD)

· French State Doctorate in Medicine – University of Rouen, France (2012)

· MD thesis awarded with highest academic distinction with committee commendation

 

French Board Certifications:

· Medical Oncology

· Clinical Hematology

 

Residency & Fellowship in Medical Oncology and Clinical Hematology (France)

· Rouen University Hospital & Henri Becquerel Cancer Center, France (2008–2012)

· Multidisciplinary training across Oncology, Clinical Hematology and Bone Marrow Transplantation / Hematopoietic Stem

Cell Transplantation, Internal Medicine

 

Postdoctoral Fellowship in Leukemia

· MD Anderson Cancer Center, Houston, Texas, USA (2015–2016)

· Focus: Therapeutic resistance and biomarker development in the MDS and AML setting.

 

Former Senior Consultant Medical Oncologist at Gustave Roussy Cancer Center (France)

· Department of Clinical Hematology and Bone Marrow Transplantation (2013–2015)

· Department of Cancer Medicine (2016–2022)

PhD in Public Health and Molecular Oncology

· University of Paris-Saclay, France (2021)

· PhD thesis awarded summa cum laude with committee commendation

MSc in Clinical Research

· University of Paris VI (Pierre and Marie Curie), France (2017)

· Major: Methodology in clinical trials and biostatistics

University Diplomas (DU)

· Clinical Oncology – University of Paris XI (2013)

· Allogeneic Hematopoietic Stem Cell Transplantation – University of Paris VI (2014)

· Personalized Medicine & Pharmacogenomics – University of Paris VI (2017)

· Immuno-Oncology – University of Paris-Sud / Paris XI (2019)

Professional Licensure

· French Medical Council (RPPS No. 10100558575)

· Dubai Health Authority – Consultant Medical Oncology (ID: 78019105)

Specializations

Solid Tumors

  • Gastrointestinal Cancers: Esophageal, Gastric (Stomach), Colorectal, Pancreatic, Liver (HCC), Bile Duct (Intra- and Extrahepatic Cholangiocarcinoma), Gallbladder, Neuroendocrine Tumors (NETs), Carcinoid Tumors

  • Breast Cancer: Hormone receptor–positive, HER2-positive, Triple-negative

  • Gynecologic Cancers: Ovarian, Cervical, Endometrial (Uterine), Vaginal, Vulvar

  • Genitourinary Cancers: Prostate, Bladder, Kidney (RCC & non-RCC), Testicular, Penile

  • Lung & Thoracic Cancers: Non-small cell, Small cell, Mesothelioma, Thymomas

  • CNS Tumors: Primary brain tumors, Metastatic brain disease

  • Soft-Tissue & Bone Sarcomas

Hematologic Malignancies

  • Lymphomas: Hodgkin and Non-Hodgkin (Follicular, DLBCL, Marginal Zone, T-cell)

  • Multiple Myeloma & Plasma Cell Disorders

  • Myeloproliferative Neoplasms

Advanced Therapeutic Expertise

  • Chemotherapy (IV, Oral, Intrathecal) & toxicity management

  • Immunotherapy (Checkpoint inhibitors) & toxicity management

  • Targeted therapies (TKIs, monoclonal antibodies)

  • Endocrine therapy (breast & prostate cancers)

  • Bone marrow biopsy & aspiration

  • Second opinions for complex/rare cancers

Academic Contributions & Memberships

  • 45+ peer-reviewed publications (incl. NEJM)

  • Research in molecular profiling, biomarker discovery, precision medicine

  • Committees & Memberships:

    • Scientific Committee – FFCD

    • Founder & General Secretary – FLOM

    • Member of ESMO, ASCO, ASH, EHA

Precision Oncology & Personalized Care

  • Molecular profiling & biomarker-guided treatment

  • Genomic testing (NGS, ctDNA, MSI-H, TMB, BRCA/HRD)

  • Pharmacogenomics

  • Translational & investigator-initiated research

  • Immunotherapy, targeted therapy, endocrine therapy, chemotherapy

  • Bone marrow biopsy & diagnostic procedures

  • Tumor board participation

  • Palliative care integration & survivorship programs

Supportive & Survivorship Care

  • Symptom management: pain, nausea, fatigue, cachexia, anemia

  • Oncologic emergencies: spinal cord compression, tumor lysis, febrile neutropenia

  • Palliative care & end-of-life planning

  • Fertility preservation counseling

  • Long-term survivorship & secondary cancer prevention

  • Cancer screening & preventive oncology

  • Patient education & shared decision-making

Book an appointment with Dr.Ali CHAMSEDDINE